The positive percentage of p-Akt, p-mTOR, and p-eIF4E were 68.3% (233/341), 56.9% (194/341), 71% (242/341) in NSCLC, respectively, whereas 20.9% (19/91), 15.4% (14/91), and 26.4% (24/91) in non-cancerous lung tissues (Non-CLT), respectively. Here, EIF4E is linked to non-small cell lung carcinoma.