High transcription levels of P4HB, PDIA3, PDIA4, PDIA5, PDIA6, ERP27, ERP29, ERP44, TMX1, TMX3, TXNDC5, TXNDC12, AGR3, and DNAJC10 were found in GBM tissues. The gene discussed is P4HB; the disease is glioblastoma.