Many pathways were also associated with cancer pathogenesis, invasion, and metastasis, including WNT signaling pathways, positive regulation of NF kappa B transcription factor activity, vascular endothelial growth factor receptor (VEGFR) signaling pathway, apoptotic signaling pathway, regulation of MAPK cascade, cell cycle, p53 signaling pathway, cytosolic DNA sensing, pathways in cancer, and JAK-STAT signaling pathway. The gene discussed is KDR; the disease is cancer.