Upon performing univariate analysis, it was found that age (≥70 years), sex (male), histology (squamous carcinoma), and pathological stage (III‐IV > II > I), smoking history (smoker), EGFR mutation (negative), KRAS mutation (positive), and TP53 mutation (positive), and the large number of coexisting mutations were factors related to shorter OS. Here, KRAS is linked to squamous cell carcinoma.