Additionally, an increase in miR‐422a expression was observed in SMMC‐7721 cells with DUXAP8 knockdown, whereas the expression of miR‐422a was decreased in QSG‐7701 cells with DUXAP8 overexpression, suggesting that DUXAP8 can negatively regulate miR‐422a expressions in HCC (Figure 4D). The gene discussed is DUXAP8; the disease is hepatocellular carcinoma.