Sarcomas consist of more than one hundred diverse bone and soft tissue cancers that are rare and heterogeneous, accounting for approximately 1% of adult tumours and 15% of paediatric cancers.88 The antigen PRAME is highly expressed in numerous types of sarcomas, such as synovial sarcoma, liposarcomas and myxoid/round cell liposarcoma.89, 90, 91, 92 Moreover, myxoid liposarcomas have higher levels of PRAME and NY‐ESO‐1 than other liposarcomas at both the transcriptional and translational levels. The gene discussed is PRAME; the disease is cancer.