Haematological malignancies such as CML and AML as well as lymphomas could be vulnerable to control by the immune system, and effector T cells, which recognize minor histocompatibility antigens and tumour‐associated antigens (TAAs) that are overexpressed in tumour cells, play a key role in this process.49, 50, 51, 52, 53 PRAME is overexpressed in many haematological malignancies but is absent in normal tissues. Here, PRAME is linked to chronic myelogenous leukemia, BCR-ABL1 positive.