Cervical cancer is responsible for 570 000 cancer cases worldwide, ranking fourth in incidence in 2018.24 A study showed that overexpression of PRAME in HeLa cervical cancer cells leads to an apparent change in morphology.32 Concomitantly, PRAME‐transfected HeLa cells show cytoplasmic vacuolization and blebbing. This evidence concerns the gene PRAME and cancer.