STAT3 and non-small cell lung carcinoma: To further evaluated the anti‐proliferation activity of HJC0152 in 2 human NSCLC cell lines that with high level of p‐STAT3 (Tyr705), A549 and H460 cells were treated with different concentrations of HJC0152 for 24 hours, and significant morphological changes and cell death were observed (Figure 1I and J).