These proportions are lower than those observed in study carried out in Brazil between 2006 and 2011 including adult patients with type 2 diabetes, in which 22% were using oral medications and insulin, and 13% insulin alone.( 18 ) However, our results presented values above of those observed in the study conducted in the city of Ribeirão Preto (SP) from 2006 to 2007, in which 11.4% of patients with diabetes were using insulin associated with oral medicines and 3.4% used insulin isolated.( 19 ). This evidence concerns the gene INS and diabetes mellitus.