Fridriksson et al. studied patients with head trauma, and reported that the serum level of NSE was higher in 22 patients with abnormal head computed tomography (CT) scan (26.7±21.4 ng/ml) compared to 28 patients with normal CT (17.7±7.8 ng/ml); serum concentration above 15.3 ng/ml had sensitivity of 77% and specificity of 52% in predicting the presence of abnormal brain CT finding (18). The gene discussed is ENO2; the disease is injury.