Our Pan-NETs cases were diagnosed clinically and resected by our surgeon at the University of Kansas Medical Center, the late Dr Stan Friesen, who screened for serum PP levels after a high-protein meal among the family members of MEN-1 [19,20], yielding a higher percentage of gastrinoma and PPoma cases than the other studies. The gene discussed is PPY; the disease is gastrin-producing neuroendocrine tumor.