In the normal pancreatic islets, β-cells were lesser immunostained for CgA than other three non-β-cells as described previously [1,13] (Figure 1) and insulinomas were relatively weaker immunostained for CgA than non-β-cell tumors but as strongly stained for SPY as in non-β-cell tumors (Table 1, Cases 7 and 9). The gene discussed is CGA; the disease is pancreatic insulinoma.