On the other hand, increased fat mass is associated with chronic inflammation and induces negative metabolic effects such as impaired glucose tolerance and deranged lipid profile.38 These increased inflammation and negative metabolic effects may lead to structural changes in the kidney, such as mesangial expansion and renal fibrosis.39 Supporting this notion, the present study demonstrated that the levels of CRP, LDL‐C, and triglyceride were significantly higher in subjects with a low MF ratio. This evidence concerns the gene CRP and renal fibrosis.