Some cytokines, such as IL‐6, were accumulated in the tumour microenvironment and induced the expression of immune molecules, such as PD‐L1, which further aggravated the tumour development.28, 29, 30 Therefore, it was worth exploring whether TIM‐4 expression was regulated by IL‐6 in NSCLC cells. The gene discussed is CD274; the disease is non-small cell lung carcinoma.