Our previous studies showed that T‐cell immunoglobulin domain and mucin domain 4 (TIM‐4), closely related to poor NSCLC prognosis, could promote the growth, proliferation and cell cycle progress of NSCLC cell lines through the interaction of its RGD motif.10 However, the role of TIM‐4 in NSCLC metastasis and EMT has not been reported. This evidence concerns the gene TBXT and non-small cell lung carcinoma.