Our finding on FEZF1-AS1 upregulation in NSCLC is in agreement with previous reports on many tumour types including NSCLC39,40 and breast.41FEZF1-AS1 exerts regulatory functions at a transcriptional and post-transcriptional level, promoting cell proliferation, migration, and invasion. The gene discussed is FEZF1; the disease is non-small cell lung carcinoma.