Since activation of VEGFR1 on leukocytes promotes leukocyte recruitment which contributes to leukocyte plugging41, sunitinib MP, which block both VEGFR2 and VEGFR1 and have a long duration of action, may be ideal for treatment of diabetic retinopathy in the absence of macular edema. Here, FLT1 is linked to macular retinal edema.