And the adding of miR-203 mimic could reverse the promoting effects of NNT-AS1 on proliferation, EMT and PI3K/AKT and ERK1/2 pathways in CCLP1 and TFK1 cells, these findings were consistent with Li et al.’s study that miR-203’s low expression was occurred in CCA [17]. Here, PPFIBP2 is linked to cholangiocarcinoma.