IF dual-staining HNmMM tissue samples for the melanoma marker Melan-A and induced pluripotent stem cell markers showing expression of NANOG (A, red), SOX 2 (B, red) SOX2 (C, red), KLF4 (C, red), and c-MYC (D, red) on some Melan-A+ (A–D, green) cells within the tumor nests and some cells within the peritumoral stroma (Figure S3). The gene discussed is SOX2; the disease is melanoma.