Bhat’s group has reported the ability of AZA-ST 8a and 8c (Figure 11) to inhibit the growth of human breast cancer cell lines (MDA-MB-231, which is estrogen receptors (ER) negative and expresses mutated p53, and T47D, which is ERα positive) [46,65,66]. The gene discussed is ESR1; the disease is breast carcinoma.