GPT and chronic obstructive pulmonary disease: Another study, conducted in five chronic obstructive pulmonary disease (COPD) patients to examine the effect of solithromycin as an anti-inflammatory treatment for COPD (NCT02628769), was terminated early due to cholestatic hepatitis in one subject and alanine aminotransaminase (ALT) elevation in two others after the administration of solithromycin [54].