The biological effects dependent on genes targeted by dysregulated miRNAs in FM patients are, to different levels, involved in muscular atrophy, epilepsy and autism (miR23a-3p), myoblast differentiation and modulation of brain-derived neurotrophic factor (BDNF) expression (miR-1); myoblast differentiation (miR-133a), immune response (miR-346), brain development (miR-139-5p), neuron development, autism, and complex regional pain syndrome (miR-320p) [16]. This evidence concerns the gene BDNF and muscular atrophy.