Salivary miR-23a-3p and miR-23b-3p were overexpressed and capable of distinguishing PC patients from HC and pancreatitis (study 5 [14]) with appreciable sensitivity and specificity; considering the regulatory role in pancreatic inflammation processes, Grieco et al. [45] described how these miRNAs were found to regulate the expression of the pro-apoptotic Bcl-2 proteins DP5 and PUMA and consequent human β-cell apoptosis. The gene discussed is BCL2; the disease is pachyonychia congenita.