EIF2AK3 and diabetes mellitus: The protein level of PERK increased by 23.2% in T2DM mice (DM group) as compared to the control group, which was decreased by 4.3% and 23.8% in baicalein 40 mg/kg/d (Bal-LD) group and baicalein 160 mg/kg/d (Bal-HD) group respectively (Figure 8A,B).