ORAI1 and cardiac hypertrophy: The cardiac hypertrophy is an adaptive capacity to stress and it is regulated by the calcineurin–nuclear factor of activated T cells (NFAT) pathway, which is linked to the stromal interaction molecule 1 (STIM1)/calcium release-activated calcium channel protein 1 (Orai1)-mediated store-operated Ca2+ entry (SOCE) [84,85].