TYR and oculocutaneous albinism: Various types of oculocutaneous albinism (OCA), a series of autosomal recessive disorders, are associated with reduced pigmentation in the skin, eyes, and hair due to malfunctioning proteins involved in melanogenesis, most notably, human tyrosinase where genetic mutations occur in its corresponding gene TYR. Oculocutaneous albinism type 1 (OCA1), the most wide-spread albinism, is caused by bi-allelic mutations in the TYR gene and occurs in approximately 1:40,000 people worldwide [1].