In tumor cells, AURKA induces cell proliferation, survival and drug resistance through interacting with oncogenic pathways, such as MYC, PKC/RAF/MEK/ERK, BCR/ABL, NF-κB, Wnt/β-catenin or the PI3K/AKT pathways [136–138], modulating pro-apoptotic (BCL2, MCL1) and anti-apoptotic (BAX, BIM, PUMA, APAF) proteins [136]. This evidence concerns the gene AURKA and neoplasm.