Using this approach, a statistically significant difference in the average fold-decrease of TXNIP expression was not identified between infection groups, however, this analysis revealed that all four vCD200 N.S.-infected RM displayed 6.3-fold or higher downregulation of TXNIP expression at d28, while WT BAC-infected RM displayed much lower decreases in TXNIP expression, ranging from 1.3-fold to 4.9-fold. The gene discussed is TXNIP; the disease is infection.