Depletion of JMJD1C severely impaired proliferation of ten different AML cell lines, carrying various oncogenic fusion genes or mutations, including AML-ETO, PML-RAR, FLT3-ITD, t(3;3) with Evi-1 overexpression and JAK2V617 among others [2]. This evidence concerns the gene PML and acute myeloid leukemia.