KRAS and familial pancreatic carcinoma: It was reported that Kras mutation activates several key pathways to allow tumor cells growth and metastasis.11 The prognostic role of Kras mutation in pancreatic cancer is still controversy and inconsistent.21 It was reported that Kras mutation detected in pancreatic cancer tissues associated with worse disease‐free survival and OS compared with Kras wild‐type tumors.