SERPINB3 and squamous cell carcinoma: In consideration of this problem, we take advantage of the specific expression of the SERPINB3 gene in squamous cell carcinoma, and the rest of our team will continue to study the specificity and targeted inhibition of the pSERPINB3‐PE38KDEL plasmid in the normal oral mucosal epithelial cell lines and other OSCC cell lines.