ANCOVA of changes between groups showed a significant decrease in hs-CRP (p = 0.002) and TNF-α (p = 0.006) in the taurine group compared to the placebo group, following adjustments for baseline values, duration of T2DM, weight, and calorie intake, whereas the changes in IL-6 (p = 0.07) were not significant. The gene discussed is TNF; the disease is type 2 diabetes mellitus.