Both cases have achieved CR for more than three years.<h4>Conclusions</h4>Deletion of 3'<i>CBFB</i> in AML with inv(16) is also accompanied with deletion of 5'<i>MYH11</i> in all the cases studied by SNP microarray, suggesting that 3'<i>CBFB</i> and 5'<i>MYH11</i> were most likely deleted together as a fusion product of inv(16) instead of occurring separately. The gene discussed is MYH11; the disease is acute myeloid leukemia.