The top 20 genes were regarded as melanoma genes (CDKN2A, MC1R, NRAS, MITF, PTEN, TERT, POT1, BRAF, TP53, TYR, CDK4, MLANA, PMEL, IL2, ERCC2, IFNG, TNF, PTGS2, CDKN2B, TYRP1). This evidence concerns the gene TYRP1 and melanoma.