To explore the clinical significance of ITPKA, a tissue microarray described before were introduced 8, the LUAD tissue microarray (TMA) contain 92 tumor samples with follow up survival data, after staining with ITPKA, in the multivariant cox regression survival analysis was performed, several clinical parameters including age, gender, pathology, T stage, N stage, TNM stage and ITPKA level were enrolled. Here, ITPKA is linked to neoplasm.