Similarly, the motifs CGR (breast invasive carcinoma), CACAAR (glioblastoma multiforme), ATGWTG (lung squamous cell carcinoma), CGWCCGAA (prostate adenocarcinoma) show exclusive affinity for YY2, RUNX1, ATF4 and ZBTB7B, respectively. The gene discussed is ATF4; the disease is glioblastoma.