The genotype frequencies (cut-off P > 0.05) were in Hardy-Weinberg equilibrium (HWE) in all controls for the variants in ARHGAP15 and FAM155A. The HWE for the variant in COLQ deviated in controls (both in diverticulosis and diverticulitis-analyses p < 0.001), and was not included in further analysis. Here, ARHGAP15 is linked to diverticular disease.