DNMT3A and Bjornstad syndrome: Though it might be possible that cooperation of other oncogenic abnormalities with DNMT3A mutation in EOL-1 cells, the co-occurrence of KMT2D-PTD with DNMT3A mutation should play a role at least partly in the leukemogenesis in the current situation as DNMT3A mutations frequently coexist with KMT2A-PTD.