Conversely, flow cytometry data showed that primary AML cells with KMT2A-PTD/DNMT3A-MT expressed lower Annexin-V and propidium iodide (PI)-positive cells indicating apoptosis reduction and more viable cells relative to KMT2A-PTD/DNMT3A-WT cells (Fig. 2g, h). Here, ANXA5 is linked to acute myeloid leukemia.