Gene functions related to metabolic pathways in kidney or implicated in cancer (especially genes linked to ccRCC and hypoxia-inducible factors HIF1α and HIF2α) together with absence of expression in bone marrow and immune system, low or no expression in most tissues, and enrichment in kidney were considered favorable with respect to gene ranking. Here, EPAS1 is linked to nonpapillary renal cell carcinoma.