Our results indicated that the expression of NMU mRNA in HCC peri- and intra-tumor tissue was positively correlated with the expression of type 2 cytokine mRNA, such as IL-4 (peri-tumor: r = 0.7131, p = 0.0138, intra-tumor: r = 0.9540, p < 0.001), IL-10 (peri-tumor: r = 0.7710, p = 0.0090, intra-tumor: r = 0.8617, p = 0.0003), and IL-13 (peri-tumor: r = 0.8552, p = 0.0008, intra-tumor: r = 0.6336, p = 0.0270) (Fig. 4a-f). Here, IL4 is linked to neoplasm.