Staining for F4 80 and CD86 (M1 macrophages) as well as F4 80 and CD206 (M2 macrophages) showed for mice injected with E0771 tumor cells that, as expected, CD206-expressing M2 macrophages dominate the tumor tissue, while in areas close to the sciatic nerve also CD86− expressing M1 macrophages are seen (Supplementary Figure S6). Here, MRC1 is linked to neoplasm.