TGFB1 and myocardial infarction: In CFs from TRPA1-deficient mice the transdifferentiation evoked by TGF-β is strongly reduced; in vivo, cardiac fibrosis is reduced in TRPA1-KO mice after myocardial infarction but is increased in WT mice treated with the TRPA1 agonist cinnamaldehyde [105].