According to the most recent revision of the WHO (2016) [4], ALCL are classified as anaplastic lymphoma kinase ALK-positive large cell anaplastic lymphoma (ALK+ ALCL), ALK-negative ALCL (ALK- ALCL), breast-implant-associated ALCL (BI-ALCL), or pcALCL. This evidence concerns the gene CACNA1A and anaplastic large cell lymphoma.