However, in the paper of Allred and Kilgore the differential responsiveness to their corresponding agonists rosglitizone and 9-cis RA by PPARγ - RXRα was found among breast, colon, and lung cancer cell lines and correlated with the differential ratio of PPARγ and RXRα present in these cancer cell lines [213]. This evidence concerns the gene PPARG and lung carcinoma.