Nevertheless, although Clusterin, CypB, Gal-1, UBE3A, and MMP-2 were not found to be directly interconnected, its presence on MSCs secretome has also been correlated with positive and promising effects on PD modeling and repair, namely through the modulation of oxidative stress and neuroinflammation, mitochondrial dysfunction prevention, and alpha-synuclein degradation, thereby exerting neuroprotective properties in PD-related environments [77,78,79,80,81]. This evidence concerns the gene UBE3A and Parkinson disease.