However, more recent data from SWOG 1312 trial (a phase 1 study investigating inotuzumab in combination with cyclophosphamide, vincristine and prednisone for R/R CD22+ B-ALL) showed that 60% of patients with Ph-like signature achieved a CR state post-therapy (13 patients) [39]. The gene discussed is CD22; the disease is acute lymphoblastic leukemia.