LDLR and metabolic dysfunction-associated steatohepatitis: Another strategy for the investigation dietary-induced NASH was reported, whereby livers from mice with a disrupted LDL receptor gene (Ldlr-null) that had been fed a western diet (WD; 17% energy as protein, 43% as carbohydrate, 41% as fat, and 0.2% as cholesterol; supplemented with olive oil) were examined.