The multivariate logistic regression analysis using parameters with p < 0.10 by univariate analysis (elevated SNX16-Ab level and severe OSA) revealed significant correlation between elevated SNX16-Ab level and the history of CAD (OR: 8.61, 95% CI: 2.07–45.0, p = 0.003). Here, SNX16 is linked to obstructive sleep apnea syndrome.