Although we only could perform this analysis in part of the patients, a significant increase in the expression levels of EPCAM, SNAIL1, CD44, CDH1, TIMP1 and BCL11A was found in the primary tumor and metastases with respect to nontumoral tissue, reinforcing their possible role during both the tumor formation and spread (Figure S3A). This evidence concerns the gene SNAI1 and neoplasm.