Our group highlighted in this regard that immune suppression measured in ascites is reduced after neoadjuvant chemotherapy [32], and that carboplatin-paclitaxel can render the cytokine profile in serum of ovarian cancer patients less immunosuppressive, through a decrease in interleukin-10, VEGF, transforming growth factor-β, and arginase [33]. The gene discussed is VEGFA; the disease is ovarian carcinoma.