Proteins recognized as mediators of paracrine senescence in pEOCs were previously found to exert a similar effect in fibroblasts (GRO-1 [46]), neuronal progenitors (GRO-1 [47]), peritoneal mesothelial cells (TGF-β1 [48]), hepatocellular cancer cells (TGF-β1 [49]), and lung adenocarcinoma cells [50]. Here, CXCL1 is linked to hepatocellular carcinoma.