IL10 and infection: Likewise, the number of polymorphonuclear cells (PMN), which were also documented to contribute to trypanosome-infection associated pathogenicity [22], were found to progressively increase in all groups as the infection progresses, yet reaching significantly higher levels in TgAlbCre-IL10-/- mice at the later infection stages than in WT and LysM-IL-10-/- mice (Fig 4B).