We could distinguish acute and subclinical infections in the 3rd trimester by the unique presence of immunity-related KEGG pathways such as cytokine-cytokine receptor interaction, antigen processing and presentation and hematopoietic cell lineage during subclinical infection and complement and coagulation cascades, epithelial cell signaling in Helicobacter pylori infection (NFKBIA, JUN, ATP6V1G1,CXCR1,ATP6V1F, IL8 genes) in the acute disease (Fig 7B). This evidence concerns the gene ATP6V1G1 and infection.