CPSF3 and cancer: For example, reports revealed DDX21 could affect the proliferation of GC cells by up‐regulating levels of cyclin D1 and CDK2. 33 Likewise, the suppression of EIF3B inhibits the proliferation and metastasis of GC by effectively modulating the expression of cancer‐related genes.34 Likewise, we also found 15 co‐expression relationships in RBP interactions such as CPSF3, DDX18, DKC1, and FUS (Table S4).