CDC6 and neoplasm: The role of senescence as a tumourigenic barrier was further augmented with the outlining of oncogene‐induced senescence (OIS).13, 18, 19, 20, 21 The phenomenon of senescence needs to be overcome in order for tumours to progress, as postulated by the oncogene‐induced DNA damage model for cancer development.22 It is crucial that the relationship between Cdc6 and senescence is interrogated, elucidating the role of Cdc6 not only in its capacity as an oncogene but also as a molecule to be exploited in inducing senescence.